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<p>US and Israeli leaders speak a day after Netanyahu again rejected notion of Palestinian statehood, their first call in almost a month See all our Middle East crisis coverage The Palestinian Red Crescent Society (PRCS) has said the humanitarian situation in northern Gaza &#8220;remains dire&#8221;, with people returning to &#822

<p>Shadow foreign secretary says Israeli president must explain how post-conflict Gaza will operate Middle East crisis – live updates The shadow foreign secretary, David Lammy, has described Benjamin Netanyahu’s opposition to the establishment of a Palestinian state when the war in the Middle East ends as “unacceptable”

<p>Dental union says region will be ‘disproportionately’ affected by EU amalgam phase-out as health service is weakest in UK Concerns have been raised about the future availability of silver dental fillings in Northern Ireland due to an imminent phasing out of the amalgam across the EU. The plan to phase out amalgam by 1 January [

<p>Exclusive: London mayoral elections in May will be ‘toughest fight yet’, Khan will tell Fabian’s Society conference Sadiq Khan will urge voters not to “let the Tories do to London what they’ve done to our country”, as he hits out at the “hollow, desperate and divisive narrative” put forward b

<p>Exclusive: Shortages of riluzole, which can delay the onset of ventilator dependence, were flagged to DHSC in September The health secretary, Victoria Atkins, has been accused of failing to ensure the supply of the only drug that can lengthen the lives of motor neurone disease sufferers by months despite officials being alerted to a shorta

<p>MEPs react to ‘tragic’ findings revealing UK falling behind EU in key environmental policies since Brexit Brexit divergence from EU destroying UK’s environmental protections Northern Ireland ‘dirty corner of Europe due to lack of governance’ Explainer: UK environmental protections dropped since Brexit European